Amazonian useful plants described in the book "Le Pays des Amazones" (1885) of the Brazilian propagandist Baron de Santa-Anna Nery: a historical and ethnobotanical perspective.

BACKGROUND: Frederico José de Santa-Anna Nery (1848-1901) was a Brazilian Baron who referred to himself as a "volunteer propagandist" for Brazil in Europe, serving as an immigration agent to publicize the living conditions in the Amazon region, advocating for its development and modernization at the end of the nineteenth century. Santa-Anna Nery's most famous book is "Le Pays des Amazones" (The Lands of the Amazons), first published in 1885, which the author dedicated a chapter to introduce and report on the Amazonian useful plant species and its relationship with humans. The aim of this work is to understand the historical context and ethnobotanical value of the plant species in the Brazilian Amazon at the end of the nineteenth century through an analysis of the book "Le Pays des Amazones" (1885) by Baron de Santa-Anna Nery, as well as to bring to light the historical importance of this very influential propagandist, who has been forgotten nowadays. METHODS: The original book "Le Pays des Amazones" (1885), as well as the original 3rd edition and its translated version into Portuguese, was carefully analyzed and all information about plants was systematized, with botanical names being updated. Finally, using the scientific name of medicinal plants alone or in combination with their traditional use, a search was carried out in databases in order to indicate current pharmacological studies that provide evidence about the described traditional uses. RESULTS: A total of 156 plant species were identified in the book, although 132 species had their scientific names updated. These species belong to 45 different families, with Fabaceae and Arecaceae the most represented, and 109 plants are Brazilian native. Considering only the 36 medicinal plants, the main medicinal indications reported were astringent, purgative/laxative, stimulant and tonic, vermifuge, febrifuge, sudorific, emetic, diuretic and antidysenteric. Regarding other useful plants (non-medicinal), 97 species were cited for food, constructions and buildings, spices and condiments, ornaments and objects, carpentry, textile fibers, gums, oils, balms and essences, pigments and tanning, hunting and fishing. CONCLUSIONS: When the book "Le Pays des Amazones" is analyzed from a timeless perspective, with a particular focus on historical ethnobotany, it is possible to observe the economic, social, and political importance of many useful plants for the Amazon at the end of the nineteenth century and how the relationship between local people, indigenous communities, and immigrants was established with plant biodiversity.

Female naturalists and the patterns of suppression of women scientists in history: the example of Maria Sibylla Merian and her contributions about useful plants.

BACKGROUND: This work reunites many women naturalists who registered knowledge about native flora in scientific expeditions around the globe between the seventeenth and nineteenth centuries. Since male naturalists are more recognized in this period of time, we aimed to list female naturalists that published plant descriptions and observations, focusing on the work of Maria Sibylla Merian and to analyze her trajectory as an example to discuss the patterns of the suppression of women scientists. A second aim was to inventory the useful plants described in Maria Sibylla's Metamorphosis Insectorum Surinamensium and find pharmacological evidence about the traditional uses described for those plants cited as medicinal and toxic. METHODS: A survey of female naturalists was carried out by searching information in Pubmed, Scielo, Google Scholar and Virtual Health Library. Once Maria Sibylla published her book Metamorphosis Insectorum Surinamensium by her own, without male co-authors, and also this book is one of the only to have text and illustrations altogether and there are reports indicating information on useful plants in this work, she and her book were chosen as subject of this research. All the information was tabulated by dividing the plants into food, medicinal, toxic, aromatic or other uses. Finally, with the combinations of the scientific name of medicinal and toxic plants with information about their popular uses, a search was carried out in databases in order to indicate current pharmacological studies that reported evidences about the traditional uses described. RESULTS: We found 28 women naturalists who participated in scientific expeditions or trips, or in a curiosity cabinet, or who were collectors of Natural History between the seventeenth and nineteenth centuries. All these women illustrated botanical species and/or recorded their everyday or medicinal use or reported their observations in the form of a published work, letters or diaries. Also, the trajectory of Maria Sibylla Merian revealed that her scientific relevance has been neglected from the eighteenth century by mechanisms of suppression, most of the time by male depreciation, which can be seen as a pattern for suppression of women in science. However, Maria Sibyllas' contributions have been valued again in the twenty-first century. In Maria Sibylla's work, 54 plants were identified, 26 of them used for food, 4 of them aromatic, 8 medicinal, 4 toxic and 9 other uses. CONCLUSION: This study evidences that there are female naturalists whose work could be an important source for ethnopharmacological studies. Researching about women scientists, talking about them and highlighting the gender bias present in the scientific academy about the way the history of science is told is essential for the construction of a more diverse and richer scientific academy. The traditional use of 7 of 8 medicinal plants and 3 of 4 toxic plants reported was correlated with pharmacological studies, highlighting the importance of this historical record and its potential to direct strategic research in traditional medicine.

The rise and fall of mandrake in medicine.

ETHNOPHARMACOLOGICAL RELEVANCE: Mandrake (Mandragora sp.) is one of the most famous medicinal plants. It has been in continuous medical use throughout written history and is still in use today in popular medicine. AIM OF THE STUDY: Mandrake derived drugs once played an important role in medicine and in magical practices. Today, the role of mandrake in popular medicine is marginal. However, natural products present in mandrake such as atropine and scopolamine, as well as their semi synthetic derivatives continue to hold and important role in medicine. Here we aim to trace the development of historical rationales and scientific events that led to the abandonment of mandrake as a medicine. MATERIALS AND METHODS: We review the medicinal uses of mandrake drugs since antiquity in an attempt to pinpoint use patterns that were popular in certain periods of time and others that are more general. We compare the uses from the native territories to those from regions where the plant got introduced and use literature reporting mandrake's chemistry and pharmacology in order to explain the diachronic changes of use patterns. RESULTS AND CONCLUSION: We found information about 88 different medicinal uses for mandrake, grouped into 39 conditions. According to the number of different medicinal uses, the most versatile period was the medieval (37), followed by the Renaissance (31), the classical (27), and the modern period (21). Considering the higher number of textual sources and use-records collected for the Renaissance period, the decrease of versatility in comparison to the medieval period appears robust. This seems to indicate a more consolidated use pattern, that might be conditioned by the reproduction of classic textual sources as well as by a less experimental approach and reduced popularity of mandrake in medicine. The introduction of the volatile anaesthetics with more reliable narcotic effects set the seal on using mandrake in surgery but opened the way for atropine being used as a prophylactic and antidote during surgical interventions.

Ethnobotanical profiles of wild edible plants recorded from Mongolia by Yunatov during 1940-1951.

Mongolian traditional botanical knowledge has been rarely researched concerning the ethnobotany theory and methodology in the last six decades (Pei in Acta Botanica Yunnanica 135-144, 1988, as reported (Martin in Ethnobotany: A methods manual, Chapman and Hall, 1995)). However, most of the known literature of indigenous knowledge and information regarding the use of local wild plants among Mongolian herders was first documented by several botanical research of Russian researchers in Mongolia through the 1940s and 1950s. One of the most comprehensive works was completed by A. A. Yunatov (1909-1967), which is known as "Fodder Plants of Pastures and Hayfields of the People's Republic of Mongolia" (FPM). Yunatov's research sampled forage plants in Mongolia from 1940 to 1951 and subsequently published a study in 1954. The original transcript of FPM was later translated into Chinese and Mongolian (Cyrillic alphabet) during 1958 and 1968. In addition to morphological characteristics, distribution, habitat, phenology, palatability, and nutrition of forage plants, Yunatov`s record collected local names, the folk understanding and evaluation of the forage, as well as other relevant cultural meanings and the use of local wild plants (collected from the wild as opposed to cultivated plants) in FPM through interviews. The book contains the most precious records created in the 1940s and 1950s on folk knowledge of the Mongolians' wild plants in Mongolia. It was composed of 8 chapters and 351 pages in total. The fifth chapter of FPM, entitled "The systematic overview of forage plants," making up 272 pages (77.49% of the total page counts). The order and content of the book-oriented along with profiles of specific plants. Yunatov collected detailed information on plants, such as the local name, morphology, distribution, habitats, ecological characteristics, and phenology. He also discussed the palatability of livestock, particular forage use, other usages, and chemical composition. Through careful reading and understanding of all three versions of the book (in Russian, Chinese, and Mongolian (Cyrillic alphabet)), the FPM-listed information of edible plants was categorized using ethnobotanical dependent analysis. The list of edible plants was ranked based on purposes and ethnobotanical inventories as per methodology and analysis used in the ethnobotany research. FPM listed 35 species are part of 15 families and 25 genera of wild edible plants. Most species belong to Liliaceae and Allium. Naturally grown grain and some food substitutes (plants that could be used as substitutions for typical food) come from the starchy organs, such as seeds, bulbs, roots, and rhizomes of 12, accounting for 34.28% of all species. Wild vegetables come from the parts of a young plant, tender leaves, young fruits, lower leg of stems, and bulbs of 9 species, accounting for 25.71% of all species. There are only three species of wild fruits, accounting for 8.57% of all edible plant species. Tea substitutes consist of leaves, roots, follicle, and aboveground parts of 8 wild plant species, accounting for 22.85% of all species. Seasonings from the wild were made of the elements such as seeds, rhizomes, tender leaves of 7 species, accounting for 20.00% of all species (Fig,8). Similarities and differences are noticeable in utilizing wild edible plants among Mongolian populations living in Mongolia and Inner Mongolia. Six species of wild edible plants listed in FPM have been proven to be collected and consumed by Mongolians from the Genghis Khan era in the twelfth century to the present day. This proved that the Mongolians have a tradition of recognizing and utilizing wild plants, demonstrating historical and theoretical value. Seven species of plants mentioned in this book were closely correlated to the locals' processing of traditional dairy products, meat, and milk food. Yunatov was not an ethnobotanist, but his accurate documentation of interviews and surveys with Mongolians represents valuable information about the collection and consumption of local wild plants during 1940-1951 in Mongolia. His research mission meant to focus on forage grass, the feed plant that sustained livestock, while he also recorded plants consumed by humans. His records on the edible parts and intake methods of some plants are incomplete. Still, it provided ethnobotanical materials of a remarkable scientific value and a living history of ethnobotany in Mongolian regions. Even by today`s standards, it will be challenging to obtain first-hand information of the richness and to the extent of Yunatov's research.

Archaeobotanical evidence of the use of medicinal cannabis in a secular context unearthed from south China.

ETHNOPHARMACOLOGICAL RELEVANCE: As one of the first plants used by ancient people, cannabis has been used for medicinal purposes for thousands of years. The long history of medicinal cannabis use contrasts with the paucity of archaeobotanical records. Moreover, physical evidence of medicinal cannabis use in a secular context is much rarer than evidence of medicinal cannabis use in religious or ritual activities, which impedes our understanding of the history of medicinal cannabis use. AIM OF THE STUDY: This study aims to provide archaeobotanical evidence of medicinal cannabis use and analyse the specific medicinal usage of cannabis in a secular context in ancient times. MATERIALS AND METHODS: Plant remains were collected from the Laoguanshan Cemetery of the Han Dynasty in Chengdu, South China, with the archaeological flotation process and were identified based on morphological and anatomical characteristics. The examination of the medicinal significance of the remains relied on the investigation of the documentation on unearthed medical bamboo slips, the diseases of the tomb occupants, the cemetery's cultural background and Chinese historical records. RESULTS: The botanical remains were accurately identified as cannabis. More than 120 thousand fruits were found, which represents the largest amount of cannabis fruit remains that have been statistically analysed from any cemetery in the world thus far. The cannabis fruits are suspected to have been used for medical purposes in a secular context and were most likely used to stop severe bleeding of the uterus and treat lumbago and/or arthralgia. CONCLUSIONS: The cannabis fruit remains reported here likely represent the first physical evidence of medicinal cannabis use for the treatment of metrorrhagia, severe lumbago, and/or arthralgia. This study emphasizes the importance of the evidence of the diseases suffered by the occupants of the tomb in determining the medicinal use of cannabis in a secular context and contributes to a comprehensive understanding of the ancient history of medicinal cannabis.

The name to remember: Flexibility and contextuality of preliterate folk plant categorization from the 1830s, in Pernau, Livonia, historical region on the eastern coast of the Baltic Sea.

ETHNOPHARMACOLOGICAL RELEVANCE: Research on the folk categorization of nature in preliterate societies in Europe is complicated due to the fragmentation of the information available and is rarely undertaken. Yet the data is valuable and may provide, in certain circumstances, important insights, if not into novel medicines, then into the historical logic of selection and memorisation of plants useful from a medicinal perspective. AIMS OF THE STUDY: We aim to understand the ethnobotany of a preliterate society by analysing the emic (derived from people) perspective on nature-related culture of one of Europe's smaller nations, whose written language and culture was shaped in the 18th-19th centuries by other, larger nations of Europe, and thus from the etic (academic) perspective. We attempt to identify how folk categorization is reflected in the relationships between plant names and uses and to map the structure of those relationships. DATA AND METHODS: We base our analysis on one of the oldest ethnobotanical manuscripts and herbaria of the Baltic governorates, compiled in 1831 by an amateur botanist, Baltic German Pastor Johann Heinrich Rosenplänter (1782-1846), which was derived from conversations with his parishioners from the tiny Pärnu parish. The historical dataset was critically analysed from an ethnobotanical perspective in light of recent identifications of the herbarium specimens. RESULTS: Although the Rosenplänter collection is fragmentary, the logic of plant categorization by non-literate peasants at that time is clearly seen in the data. Plants preserved in the herbarium were predominantly used for ethno-medicinal, food or ethno-veterinary purposes, such as treating chronic skin and joint diseases as well as severe acute diseases in humans and animals. Among 129 folk taxa analysed, more than one third had apparent purpose-related plant names providing clear links to their use, whereas a few multifunctional plants had several names reflecting diverse uses. For example, Hypericum spp., which was used in three different ways, had three semantically distinct names. However, among the plants that Rosenplänter collected, there were also some that were simply named and described by people but lacked any usability data (e.g., Trollius europaeus), meaning that use as such was not the primary criterion for recognising a plant. The web-like structure of preliterate thinking in plant-related knowledge reveals a deep relationship with the environment and the interpretation of new elements through familiar natural objects. CONCLUSION: Our findings demonstrate that historical ethnobotanical data, if thoughtfully analysed, can be used not only for comparative purposes, but also for understanding the logic of preliterate thinking. We encourage future in-depth studies of historical ethnobotanical data in Europe in order to understand the relationship between nature and culture of native European populations.

"It may also have prevented churchgoers from falling asleep": southernwood, Artemisia abrotanum L. (fam. Asteraceae), in the church bouquet, and its contemporary presence as a heritage plant in Sweden.

INTRODUCTION: Southernwood, Artemisia abrotanum L., is a plant that has been cultivated for centuries. Most probable is that it has its origin in the eastern Mediterranean area. It has been kept for its fragrance and has a history of being a medicinal and insect-repellent plant. In earlier centuries, the plant was commonly found in peasants' gardens in Sweden and utilised especially as a component in the bouquets brought to church by women. The aim of this article is to bring together data about Artemisia abrotanum and to summarise its cultural history and folk botanical importance. In Sweden, it is still grown in some gardens in the countryside and is esteemed for its fragrance. METHODS: In the early twentieth century, various folklore archives in Sweden (Lund, Uppsala) distributed questionnaires about the use of church bouquets. These records provided interesting information about the importance of southernwood and other species. We have also used data found in ethnographic records and local historical reports. Between 2007 and 2017, a nationwide inventory organised by the Programme for Diversity of Cultivated Plants (POM) documented and gathered several heirloom varieties of southernwood. RESULTS AND DISCUSSION: Together with a few other domestic plants of foreign origin (e.g. Lavandula angustifolia Mill., Tanacetum balsamita L., and Tanacetum vulgare L.), Artemisia abrotanum has been cultivated throughout Sweden in peasants' gardens as a medicinal plant and for its fragrance. According to the sources, Artemisia abrotanum was one of the most common species cultivated by the Swedish peasantry. Although used in folk medicine and to some extent as a repellent, it was most esteemed for its fragrance. Peasant women would carry a twig of the plant in the obligatory church bouquet or in the hymnal when attending the services in the Lutheran church on Sundays. In Sweden, this custom with the church bouquet has been known since the time of the Reformation in the sixteenth century and survived until the late nineteenth century, when major changes took place in connection with industrialisation, modernisation, secularisation and urbanisation. Although the custom with the church bouquet disappeared, nationwide inventories conducted by the Programme for Diversity of Cultivated Plants in 2007-2015 revealed that the plant still exists in many gardens on the countryside throughout Sweden as a cultural relict and reminiscence plants. People care for the plant, have sentiments for it and it is spread from person-to-person. Several heirloom varieties have been discovered, which will be preserved ex situ for the future. CONCLUSIONS: Southernwood was probably the most commonly used herb in the peasant women's church bouquet until the end of the nineteenth century. It had a satisfying fragrance and was easy to grow. Although the custom has disappeared, the plant has survived until the present day in many gardens as a reminiscence of the custom of former times.

The 'enigma' of Richard Schultes, Amazonian hallucinogenic plants, and the limits of ethnobotany.

This story is about the twentieth-century ethnobotanist, Richard Evans Schultes (1915-2001), and his research on hallucinogenic plants. Ethnobotany can contribute directly to science and technology studies in that the discipline makes cultural ways of knowing its scientific subject. Ethnobotanists must learn about plants through people, and are not able to conceal their interactions with indigenous informants and other ethnobotanists. I focus on an 'enigma' that Schultes presented, concerning the peculiar ability of indigenous Amazonians to distinguish between local varieties of vine that he was unable to tell apart, notably those used to prepare the hallucinogenic beverage ayahuasca. The enigma describes a complicated and irresolvable question thrown up at the uneasy intersection between different ways of knowing about the world, and shows how modern scientific travellers might navigate - or fail to navigate - the uncertain passage between them. Together with Schultes's accounts of his own non-ordinary states of consciousness elicited by ayahuasca, and his writings on the Victorian botanist Richard Spruce, I chart an epistemological gulf between Schultes's modern scientific cosmology and that of his Amazonian informants. In describing his inability to learn about the ayahuasca varieties from Amazonians, Schultes's enigma traces the very limits of the ethnobotanical discipline and reveals the fragility of the processes by which scientific naturalists might impose categories such as 'nature' and 'culture'.

Marcgrave and Piso's plants for sale: The presence of plant species and names from the Historia Naturalis Brasiliae (1648) in contemporary Brazilian markets.

ETHNOPHARMACOLOGICAL RELEVANCE: Parallelisms between current and historical medicinal practices as described in the seventeenth century treatise Historia Naturalis Brasiliae (HNB) provide us with an overview of traditional plant knowledge transformations. Local markets reflect the actual plant use in urban and rural surroundings, allowing us to trace cross-century similarities of ethnobotanical knowledge. AIMS OF THE STUDY: We aim to verify in how far the HNB, created in seventeenth-century northeastern Brazil, correlates with contemporary plant use in the country by comparing the plant knowledge therein with recent plant market surveys at national level. MATERIALS AND METHODS: We conducted a literature review on ethnobotanical market surveys in Brazil. We used the retrieved data on plant composition and vernacular names, together with our own fieldwork from the Ver-o-Peso market in Belém, to compare each market repertoire with the useful species in the HNB. We analyzed similarities among markets and the HNB with a Detrended Correspondence Analysis and by creating Venn diagrams. We analyzed the methods of the different markets to check whether they influenced our results. RESULTS: Out of the 24 markets reviewed, the greatest similarities with the HNB are seen in northern Brazilian markets, both in plant composition and vernacular names, followed by the northeast. The least overlap is found with markets in the central west and Rio de Janeiro. Most of the shared vernacular names with the HNB belonged to languages of the Tupi linguistic family. CONCLUSION: The similarity patterns in floristic composition among Brazilian markets and the HNB indicate the current wider distribution and trade of the species that Marcgrave and Piso described in 1648 in the northeast. Migration of indigenous groups, environmental changes, globalized and homogenous plant trade, and different market survey methods played a role in these results. The HNB is a reference point in time that captures a moment of colonial cultural transformations.

Ethnoveterinary botanical medicine in South Africa: A review of research from the last decade (2009 to 2019).

ETHNOPHARMACOLOGICAL RELEVANCE: Ethnoveterinary medicine (EVM) practices remain a common feature of South African animal husbandry, particularly in rural livestock healthcare. This review provides an update of research undertaken on South African EVM from 2009 until 2019. AIM OF THE STUDY: This review collates information and investigates trends in the increasing field of EVM research in South Africa over the last decade. MATERIALS AND METHODS: A literature search was conducted using available databases including ScienceDirect, PubMed, Scopus and Google Scholar. Dissertations, theses, books and technical reports were also searched. RESULTS: In the past decade, ethnoveterinary surveys conducted in South Africa report the use of 139 plants from 50 families used against 21 animal diseases and conditions. Leaves, roots and bark have remained popular plant parts used for EVM. In terms of livestock species reported, the major focus was on cattle, goats and poultry. Only four of the nine provinces in the country have been surveyed. CONCLUSIONS: Relatively few publications reporting on ethnoveterinary surveys have originated from South Africa. These papers refer to many plants used for a variety of commonly encountered animal diseases and afflictions. With reference to recently published guidelines on conducting ethnobotanical surveys, several recommendations can be made to improve the robustness of surveys documenting the use of plants for EVM in South Africa.

Inventing a herbal tradition: The complex roots of the current popularity of Epilobium angustifolium in Eastern Europe.

ETHNOPHARMACOLOGICAL RELEVANCE: Currently various scientific and popular sources provide a wide spectrum of ethnopharmacological information on many plants, yet the sources of that information, as well as the information itself, are often not clear, potentially resulting in the erroneous use of plants among lay people or even in official medicine. Our field studies in seven countries on the Eastern edge of Europe have revealed an unusual increase in the medicinal use of Epilobium angustifolium L., especially in Estonia, where the majority of uses were specifically related to "men's problems". THE AIM OF THE CURRENT WORK IS: to understand the recent and sudden increase in the interest in the use of E. angustifolium in Estonia; to evaluate the extent of documented traditional use of E. angustifolium among sources of knowledge considered traditional; to track different sources describing (or attributed as describing) the benefits of E. angustifolium; and to detect direct and indirect influences of the written sources on the currently documented local uses of E. angustifolium on the Eastern edge of Europe. MATERIALS AND METHODS: In this study we used a variety of methods: semi-structured interviews with 599 people in 7 countries, historical data analysis and historical ethnopharmacological source analysis. We researched historical and archival sources, and academic and popular literature published on the medicinal use of E. angustifolium in the regions of our field sites as well as internationally, paying close attention to the literature that might have directly or indirectly contributed to the popularity of E. angustifolium at different times in history. RESULTS: Our results show that the sudden and recent popularity in the medical use of E. angustifolium in Estonia has been caused by local popular authors with academic medical backgrounds, relying simultaneously on "western" and Russian sources. While Russian sources have propagated (partially unpublished) results from the 1930s, "western" sources are scientific insights derived from the popularization of other Epilobium species by Austrian herbalist Maria Treben. The information Treben disseminated could have been originated from a previous peak in popularity of E. angustifolium in USA in the second half of the 19th century, caused in turn by misinterpretation of ancient herbals. The traditional uses of E. angustifolium were related to wounds and skin diseases, fever, pain (headache, sore throat, childbirth), and abdominal-related problems (constipation, stomach ache) and intestinal bleeding. Few more uses were based on the similarity principle. The main theme, however, is the fragmentation of use and its lack of consistency apart from wounds and skin diseases. CONCLUSIONS: Historical ethnobotanical investigations could help to avoid creating repeating waves of popularity of plants that have already been tried for certain diseases and later abandoned as not fully effective. There is, of course, a chance that E. angustifolium could also finally be proven to be clinically safe and cost-effective for treating benign prostatic hyperplasia, but this has not yet happened despite recent intensive research. Documented traditional use would suggest investigating the dermatological, intestinal anti-hemorrhagic and pain inhibiting properties of this plant, if any.

Medicinal plants of the Bible-revisited.

BACKGROUND: Previous lists number from 55 to 176 plant species as "Biblical Medicinal Plants." Modern studies attest that many names on these lists are no longer valid. This situation arose due to old mistranslations and/or mistakes in botanical identification. Many previously recognized Biblical plants are in no way related to the flora of the Bible lands. Accordingly, the list needs revision. METHODS: We re-examine the list of possible medicinal plants in the Bible based on new studies in Hebrew Biblical philology and etymology, new studies on the Egyptian and Mesopotamian medicinal use of plants, on ethnobotany and on archaeobotany. RESULTS: In our survey, we suggest reducing this list to 45 plant species. Our contribution comprises 20 "newly" suggested Biblical Medicinal Plants. Only five species are mentioned directly as medicinal plants in the Bible: Fig (Ficus carica), Nard (Nardostachys jatamansi), Hyssop (Origanum syriacum), balm of Gilead (Commiphora gileadensis) and Mandrake (Mandragora officinarum). No fewer than 18 medicinal plants are mentioned in old Jewish post-Biblical sources, in addition to those in the Bible. Most of these plants (15) are known also in Egypt and Mesopotamia while three are from Egypt only. Seven of our suggested species are not mentioned in the Bible or in the Jewish post-Biblical literature but were recorded as medicinal plants from Egypt, as well as from Mesopotamia. It is quite logical to assume that they can be included as Biblical Medicinal Plants. CONCLUSIONS: All our suggested Biblical Medicinal Plants are known as such in Ancient Egypt and/or Mesopotamia also. Examination of our list shows that all these plants have been in continuous medicinal use in the Middle East down the generations, as well as being used in the Holy Land today. Precisely in King Solomon's words, "That which has been is what will be, that which is done is what will be done. And there is nothing new under the sun" (Ecclesiastes 1:9).

Historical perspectives of ethnobotany.

Ethnobotany is the study of the direct interaction between plants and man in his culture. From time immemorial, man has been depending on Mother Nature for all his basic needs and plant diversity that existed around him always attracted his curiosity. Man's preliminary interest in plants started from his need for food, shelter, protection and then his attention shifted to the remedies for injuries and diseases. In fact, medicine and botany always had strong and close connections, as most of the modern medicines come from plant sources. The current venture reviews the developments and perspectives of ethnobotany in global scenarios. We have summarized the available literature and documentations regarding the historic background of ethnobotany. A survey of the literature survey reveals that plant resources were cited around the globe for curing almost all disease categories i.e. skin disorders, respiratory disorders, digestive disorders, urinary disorders, cardiac disorders, ophthalmic disorders, ear nose throat (ENT) disorders, excretory disorders, nervous disorders, immunity disorders and so on. The orally exchanged customary information/knowledge is in the hands of elders, and most of it can vanish after their deaths and could lead to the depletion of such imperative information. The ethnic society resources, like the folk asset in association with a nature of investigated and surveyed areas, can be conserved through documentation. The natural chemical compounds from plants may be screened and isolated. Plants with therapeutic uses should be tested in studies by using those isolated natural compounds in laboratories to screen and evaluate of plants metabolites with potential therapeutic uses.

Historical and traditional medical applications of Carlina acaulis L. - A critical ethnopharmacological review.

ETHNOPHARMACOLOGICAL RELEVANCE: The genus Carlina (Asteraceae) comprises approx. 30 plant species growing in Europe and Asia. Carlina acaulis L. was widely used as medicine, especially in Germany and Poland. The plant root was applied e.g. to treat various skin diseases and as a diaphoretic, diuretic, and anthelmintic agent. At the end of the 19th century, the medicinal use of the plant ceased though C. acaulis roots are still used in folk medicine, especially in rural areas of the Balkans where the plant grows in the wild. AIM OF THE REVIEW: The aim of this review is to compile historical and current ethnomedical uses of C. acaulis and compare these applications with the results of modern chemical and pharmacological research of this plant. This analysis may give a lead for further research on this old, almost forgotten medicinal plant. METHODOLOGY: Historical data on the medicinal application of C. acaulis over many centuries were collected. The historical uses were compared with the contemporary indications. The present day knowledge on the chemistry and biological activity of C. acaulis is also reviewed. This information is compared with the ethnopharmacological information. RESULTS: Plants from the genus Carlina were already described by Theophrastus of Eresus, Dioscorides, Pliny the Elder, and Galen of Pergamum. Carlinae radix was still featured in Renaissance botanical books and in official pharmacopoeias, but disappeared from the scene in the 19th century. The present day information on the phytochemistry and pharmacological activity of these plants is limited. There are some data on the occurrence of common plant ingredients such as essential oil, flavonoids, phenolic acids, triterpenes, inulin, and fatty acids. However, most concern the green parts of the plant. Its medicinal use remains poorly understood, as there are only very limited results of in-vitro studies on the roots. CONCLUSIONS: The historical uses of the plant can still be found in rural areas. Yet, detailed phytochemical and pharmacological research is needed to evaluate the effectiveness and safety of the medical use of Carlina acaulis.

Medicinal plants of the Caatinga, northeastern Brazil: Ethnopharmacopeia (1980-1990) of the late professor Francisco José de Abreu Matos.

ETHNOPHARMACOLOGICAL IMPORTANCE: The Caatinga (semi-arid region), is an exclusively Brazilian biome. Considering the scarcity of ethnobotanical and ethnopharmacological studies in this region before the year 2000, this study presents data from ethnobotanical expeditions carried out between 1980 and 1990, by the late professor Francisco José de Abreu Matos (1924-2008). The information revealed in this present work are valuable and remained unpublished until now. MATERIALS AND METHODS: The objective was to organize, systematize and analyze ethnobotanical and ethnopharmacological data using ethnobotanical analytical techniques. The most cited native species in each use category were selected for literature review of the pharmacological studies related to their ethnomedicinal uses. RESULTS: Revision of the botanical nomenclature led to the botanical confirmation of 272 plants, of which 84 (30.9%) were reclassified. These represented 71 families and 220 genera that were cited 1957 times. 153 (56.3%) of these plant species are native to Brazil, of which 36 (23.4%) are endemic to the Caatinga. The use reports (RU) associated with these plants, according to the body systems (ICPC-2) in decreasing order of UR and the ICF values were respiratory system (93 species, 407 UR, ICF 0.77), digestive system (119 species, 373 UR, ICF 0.68), general and nonspecific symptoms (95 species, 219 UR, ICF 0.58), female genital system (60 species, 184 UR, ICF 0.68), skin (71 species, 156 UR, ICF 0.55), cardiovascular (50 species, 99 UR, ICF 0.50), blood and immune system diseases (46 species, 96 UR, ICF 0.53), urological (44 species, 88 UR, ICF 0.51), musculoskeletal (33 species, 80 UR, ICF 0.60), psychological (21 species, 71 UR, ICF 0.60), while others represent less than 10.0% of the UR. The most cited plants in the disease categories were Dysphania ambrosioides (28), Pombalia calceolaria (28) Hymenaea courbaril (26), Myracrodruon urundeuva (50), Brassica juncea subsp. integrifolia (16), Scoparia dulcis (22), Phyllanthus niruri (14), Egletes viscosa (25), Lippia alba (16), Erythroxylum vacciniifolium (9) and Salvia rosmarinus (21). The most prominent clades of the medicinal plants based on cluster analysis were the Lamiids (Euasterids)-497 UR and the Fabids (Eurosids I) - 468 UR. Association between certain phylogenetic clades and use-category were also observed and discussed. CONCLUSION: This study demonstrated a new approach in ethnopharmacology by mapping plant usages to diseases prevalent in a community from old ethnobotanical travel reports. In addition to revealing the therapeutic potential of Caatinga species using cluster analysis.

Accuracy of Dioscorides,' De materia medica (First Century C.E.), Regarding Diuretic Activity of Plants.

OBJECTIVES: Assess whether an ancient text on herbal medicine accurately characterizes a class of herbal diuretics. DESIGN: The Greek text of Dioscorides De materia medica was assessed for herbs stated to have diuretic activity, and then modern research was sought to determine how accurate the ancient assessment of these herbs was. RESULTS: Of the 105 plants cited as having diuretic activity by Dioscorides, 56 (53.3%) genuses are confirmed as being diuretic in animal or human research. For another 38 (36.2%) genuses, no research related to diuresis could be identified. Six (5.7%) genuses had mixed results in modern research, whereas a mere 5 (4.8%) genuses were shown to not have diuretic activity. Considering the 67 genuses that were investigated, 56 (83.6%) were confirmed. CONCLUSION: This analysis confirms that Dioscorides was accurate in determining the diuretic nature of herbs, raising the possibility that he was right about other therapeutic suggestions concerning herbs he made. For the remaining herbs that have not been assessed for diuretic effect, it is not yet known if Dioscorides was accurate. Our findings suggest that the 38 herbs Dioscorides categorized as diuretics that have not been studied for diuretic function are candidates for research in this regard.

Cultivo y usos etnobotánicos del cáñamo (Cannabis Sativa L) en la ciencia árabe (siglos VIII-XVII) / Hemp cultivation and ethnobotanical uses in arabic science (8th-17th centuries)

El cáñamo es actualmente objeto de gran interés en el ámbito de la comunidad científica desde muy diferentes perspectivas, entre ellas, la etnobotánica. Este enfoque está interesado en estudiar la difusión cultural de la planta por la acción del género humano y su relación histórica y presente con este. En el marco de la etnobotánica histórica los estudios filológicos ofrecen información muy relevante para poder reconstruir la difusión cultural de la planta, sus usos y sus productos en diferentes tiempos y espacios geográficos. Hasta el momento no se ha publicado ningún trabajo sobre el cultivo y usos etnobotánicos del cáñamo en la civilización árabe-islámica clásica. A partir de los datos extraídos de casi una treintena de fuentes científicas redactadas entre los siglos VIII y XVII, analizamos en este artículo diferentes aspectos relativos al cultivo de la planta y sus usos etnobotánicos (alimentario-dietéticos, pienso y forraje, fabricación de hilos, tejidos y cuerdas, fabricación de papel, insecticida, repelente de animales, medicamento en veterinaria, abstergente, combustible, e incienso ceremonial). La información que encontramos en nuestras fuentes nos habla de la existencia de un proceso de transmisión y continuidad de formas de cultivo y usos del cáñamo desde la Antigüedad hasta la civilización árabe-islámica (AU)

Recent years have been witness to a vast outpouring of publications on hemp from many different scientific perspectives. Among them, Ethnobotany is interested in tracking how human action determined the cultural diffusion of this plant and how human beings have interacted with it throughout history. Within the theoretical frame of historical Ethnobotany, philological studies can provide us with a great deal of relevant information as they help us to reconstruct the cultural diffusion of hemp uses and products in the context of different ages and geographical spaces. So far, there is not available any publication on cannabis cultivation and its ethnobotanical uses in Arab-Islamic civilization. In this article we analyse several different aspects concerning this topic: cultivation, harvesting, retting and fiber separation techniques, human food and culinary uses, animal feed uses, raw material for threads, robes, cloth and paper fabrication uses, insecticide, animal repellent, medication in veterinary medicine, detergent, combustible and ritual incense uses. Our research is based on the information we find in nearly thirty Arabic scientific sources written between the 7th and the 18th centuries. This information enables us to claim that hemp techniques cultivation and uses were transferred from the pre-Islamic Ancient World civilizations to the Arab-Islamic civilization (AU)

William Burroughs: Sailor of the Soul.

In 1953, William Seward Burroughs made several important and largely unrecognized discoveries relating to the composition and clinical pharmacological effects of the hallucinogenic plant potion known as yagé or ayahuasca. Illustrations of Burroughs' voucher sample of Psychotria viridis and his letter to the father of modern ethnobotany, Richard Evans Schultes, are published here for the very first time.

Tangled history of the European uses of Sphagnum moss and sphagnol.

ETHNOPHARMACOLOGICAL RELEVANCE: Sphagnum mosses and peat could have been utilized as wound dressings for centuries, however reliable data on this subject are ambiguous; sometimes even no distinction between peat moss (Sphagnum spp.) and peat is made or these terms become confused. The first scientific account on surgical use of peat comes from 1882: a peat digger who successfully, by himself and in the way unknown to the then medicine, cured an open fracture of his forearm with peat. The peat, and very soon the peat moss itself (which is the major constituent of peat) drew attention of the 19th-century surgeons. AIMS OF THE WORK: We search for reliable information on: (1) inspirations for Sphagnum usage for medical purposes and its beginnings in the 19th century, (2) substances or products named sphagnol and their connections with (1); (3) on the origin of this name, (4) and on the occurrence of this name in medical sources. MATERIALS AND METHODS: We have identified and studied published sources on the uses of peat-based and Sphagnum-based preparations and products of any processing level (including herbal stock, distillate, isolated pure or impure active principle, or a mixture of such) in surgery, pharmacy or cosmetics. A special attention was paid to the name sphagnol, which appeared many a time, in more than one context since 1899. Source publications were critically analysed from the taxonomical, pharmacognostical and ethnopharmacological points of view. Gathered data were cross-checked with the modern knowledge of the biologically active principles of Sphagnum and the prospects of their medical use. RESULTS: The application of peat in surgery started 1882. The use of peat moss as dressings was developed in the 1880's. It returned to surgical practice during WW1. The name sphagnol has two meanings: (1) A chemical substance isolated from the cell walls of Sphagnum mosses in 1899. A post-1950 research showed it to be a mixture of phenols dominated by sphagnum acid. (2) A product of dry distillation of peat contains solid and liquid fractions and was applied in skin diseases due to antiseptic properties. It was added to ointments and medicated soaps manufactured up to the late 1960's. Today none of these two sphagnols is in use. CONCLUSIONS: Surgical application of peat had an ethnopharmacological origin: a case of wound treatment with peat as a remedy rather than a dressing (1880, published 1882) shortly shifted the surgeons' attention to peat moss as an absorptive dressing. The 1880's tests of antiseptic properties of peat and peat moss failed, the sterilization methods overrode the physiological effects of Sphagnum dressings. Sphagnan, a polysaccharide from Sphagnum cell walls, discovered 1983, inhibits microbial growth, tans the collagen and removes ammonia from microbial environments. Portions of raw peat could be sterile. The isolation of sphagnol (1899) from Sphagnum cell walls was not inspired by old surgery. Main component of sphagnol, the sphagnic acid, was used clinically during WW2, but was proved a weak antimicrobial agent. A homonymous name sphagnol appeared independently for a product of dry distillation of peat, introduced commercially probably about 1899, too, which gave rise to confusions: a) the commercial, "distilled" sphagnol was not the crystalline principle of Sphagnum cell walls. 2) the "distilled" sphagnol was hardly defined technologically or pharmacologically, never standardized in terms of the substrate (a variety of peat rather than Sphagnum herb) and the production process. This sphagnol, resembling pitch or tar, was an additive to medicated soaps and ointments for skin treatment and care. It must have been a low-scale product although advertised worldwide. Neither sphagnum acid nor sphagnan are used medicinally today.